Front page
Handbook information
Part 1: Cochrane reviews
Part 2: General methods for Cochrane reviews
Part 3: Special topics
    13 Including non-randomized studies
    14 Adverse effects
    15 Incorporating economics evidence
    16 Special topics in statistics
       16.1 Missing data
       16.2 Intention-to-treat issues
       16.3 Cluster-randomized trials
       16.4 Cross-over trials
          16.4.1 Introduction
          16.4.2 Assessing suitability of cross-over trials
          16.4.3 Assessing risk of bias in cross-over trials
          16.4.4 Methods of analysis for cross-over trials
          16.4.5 Methods for incorporating cross-over trials into a meta-analysis
          16.4.6 Approximate analyses of cross-over trials for a meta-analysis
             Introductory text
             Table 16.4.a: Some possible data available from the report of a cross-over trial
             16.4.6.1 Mean differences
             16.4.6.2 Standardized mean difference
             16.4.6.3 Imputing correlation coefficients
             16.4.6.4 Example
          16.4.7 Issues in the incorporation of cross-over trials
       16.5 Studies with more than two intervention groups
       16.6 Indirect comparisons and multiple-treatments meta-analysis
       16.7 Multiplicity and the play of chance
       16.8 Bayesian and hierarchical approaches to meta-analysis
       16.9 Rare events (including zero frequencies)
       16.10 Chapter information
       16.11 References
    17 Patient-reported outcomes
    18 Reviews of individual patient data
    19 Prospective meta-analysis
    20 Qualitative research and Cochrane reviews
    21 Reviews in public health and health promotion
    22 Overviews of reviews
Additional material