Front page
Handbook information
Part 1: Cochrane reviews
Part 2: General methods for Cochrane reviews
Part 3: Special topics
13 Including non-randomized studies
14 Adverse effects
15 Incorporating economics evidence
16 Special topics in statistics
16.1 Missing data
16.2 Intention-to-treat issues
16.3 Cluster-randomized trials
16.4 Cross-over trials
16.5 Studies with more than two intervention groups
16.5.1 Introduction
16.5.2 Determining which intervention groups are relevant
16.5.3 Assessing risk of bias in studies with more than two groups
16.5.4 How to include multiple groups from one study
16.5.5 Heterogeneity considerations with multiple-intervention studies
16.5.6 Factorial trials
16.6 Indirect comparisons and multiple-treatments meta-analysis
16.7 Multiplicity and the play of chance
16.8 Bayesian and hierarchical approaches to meta-analysis
16.9 Rare events (including zero frequencies)
16.10 Chapter information
16.11 References
17 Patient-reported outcomes
18 Reviews of individual patient data
19 Prospective meta-analysis
20 Qualitative research and Cochrane reviews
21 Reviews in public health and health promotion
22 Overviews of reviews
Additional material
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