Front page
Handbook information
Part 1: Cochrane reviews
Part 2: General methods for Cochrane reviews
Part 3: Special topics
13 Including non-randomized studies
13.1 Introduction
13.2 Developing criteria for including non-randomized studies
13.2.1 What is different when including non-randomized studies?
13.2.1.1 Including both randomized and non-randomized studies
13.2.1.2 Evaluating benefits and harms
13.2.1.3 Determining which types of non-randomized study to include
13.2.1.4 Distinguishing between aetiology and effectiveness research questions
13.2.2 Guidance and resources available to support review authors
Table 13.2.a: List of study design features (studies with allocation to interventions at the
Table 13.2.b: List of study design features (studies with allocation to interventions at the group
13.2.3 Summary
13.3 Searching for non-randomized studies
13.4 Selecting studies and collecting data
13.5 Assessing risk of bias in non-randomized studies
13.6 Synthesis of data from non-randomized studies
13.7 Interpretation and discussion
13.8 Chapter information
Box 13.8.a: The Cochrane Non-Randomised Studies Methods Group
13.9 References
14 Adverse effects
15 Incorporating economics evidence
16 Special topics in statistics
17 Patient-reported outcomes
18 Reviews of individual patient data
19 Prospective meta-analysis
20 Qualitative research and Cochrane reviews
21 Reviews in public health and health promotion
22 Overviews of reviews
Additional material
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