Front page
Handbook information
Part 1: Cochrane reviews
Part 2: General methods for Cochrane reviews
5 Defining the review question and developing criteria for including studies
6 Searching for studies
7 Selecting studies and collecting data
8 Assessing risk of bias in included studies
9 Analysing data and undertaking meta-analyses
9.1 Introduction
9.2 Types of data and effect measures
9.3 Study designs and identifying the unit of analysis
9.4 Summarizing effects across studies
9.5 Heterogeneity
9.6 Investigating heterogeneity
9.6.1 Interaction and effect modification
9.6.2 What are subgroup analyses?
9.6.3 Undertaking subgroup analyses
9.6.4 Meta-regression
9.6.5 Selection of study characteristics for subgroup analyses and meta-regression
Introductory text
9.6.5.1 Ensure that there are adequate studies to justify subgroup analyses and meta-regressions
9.6.5.2 Specify characteristics in advance
9.6.5.3 Select a small number of characteristics
9.6.5.4 Ensure there is scientific rationale for investigating each characteristic
9.6.5.5 Be aware that the effect of a characteristic may not always be identified
9.6.5.6 Think about whether the characteristic is closely related to another characteristic
9.6.6 Interpretation of subgroup analyses and meta-regressions
9.6.7 Investigating the effect of baseline risk
9.6.8 Dose-response analyses
9.7 Sensitivity analyses
9.8 Chapter information
Box 9.8.a: The Cochrane Statistical Methods Group
9.9 References
10 Addressing reporting biases
11 Presenting results and 'Summary of findings' tables
12 Interpreting results and drawing conclusions
Part 3: Special topics
Additional material
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