What
are the experimental and control (comparator) interventions of interest
Does
the intervention have variations (e.g. dosage/intensity, mode of delivery,
personnel who deliver it, frequency of delivery, duration of delivery,
timing of delivery)?
Are
all variations to be included (for example is there a critical dose below
which the intervention may not be clinically appropriate)?
How
will trials including only part of the intervention be handled?
How
will trials including the intervention of interest combined with another
intervention (co-intervention) be handled?
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