Item

Yes

No

1.

Is the study population clearly described?

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2.

Are competing alternatives clearly described?

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3.

Is a well-defined research question posed in answerable form?

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4.

Is the economic study design appropriate to the stated objective?

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5.

Is the chosen time horizon appropriate to include relevant costs and consequences?

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6.

Is the actual perspective chosen appropriate?

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7.

Are all important and relevant costs for each alternative identified?

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8.

Are all costs measured appropriately in physical units?

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9.

Are costs valued appropriately?

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10.

Are all important and relevant outcomes for each alternative identified?

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11.

Are all outcomes measured appropriately?

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12.

Are outcomes valued appropriately?

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13.

Is an incremental analysis of costs and outcomes of alternatives performed?

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14.

Are all future costs and outcomes discounted appropriately?

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15.

Are all important variables, whose values are uncertain, appropriately subjected to sensitivity analysis?

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16.

Do the conclusions follow from the data reported?

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17.

Does the study discuss the generalizability of the results to other settings and patient/ client groups?

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18.

Does the article indicate that there is no potential conflict of interest of study researcher(s) and funder(s)?

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19.

Are ethical and distributional issues discussed appropriately?

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