This is an archived version of the Handbook. For the current version, please go to or search for this chapter here.  Amendments to protocols

Any modification or edit (including withdrawal) of a published protocol gives the protocol the status of amended. It is not possible to ‘update’ a protocol. Amended protocols are re-published on the CDSR. A protocol may receive an amendment at any time. An amendment can involve much or little work, and result in big or small changes to the document.