Item

Yes

No

1.

Is the study population clearly described?

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☐

2.

Are competing alternatives clearly described?

☐

☐

3.

Is a well-defined research question posed in answerable form?

☐

☐

4.

Is the economic study design appropriate to the stated objective?

☐

☐

5.

Is the chosen time horizon appropriate to include relevant costs and consequences?

☐

☐

6.

Is the actual perspective chosen appropriate?

☐

☐

7.

Are all important and relevant costs for each alternative identified?

☐

☐

8.

Are all costs measured appropriately in physical units?

☐

☐

9.

Are costs valued appropriately?

☐

☐

10.

Are all important and relevant outcomes for each alternative identified?

☐

☐

11.

Are all outcomes measured appropriately?

☐

☐

12.

Are outcomes valued appropriately?

☐

☐

13.

Is an incremental analysis of costs and outcomes of alternatives performed?

☐

☐

14.

Are all future costs and outcomes discounted appropriately?

☐

☐

15.

Are all important variables, whose values are uncertain, appropriately subjected to sensitivity analysis?

☐

☐

16.

Do the conclusions follow from the data reported?

☐

☐

17.

Does the study discuss the generalizability of the results to other settings and patient/ client groups?

☐

☐

18.

Does the article indicate that there is no potential conflict of interest of study researcher(s) and funder(s)?

☐

☐

19.

Are ethical and distributional issues discussed appropriately?

☐

☐