This is an archived version of the Handbook. For the current version, please go to or search for this chapter here.

13.1  Introduction

13.1.1 What this chapter is about

Box 13.1.a: Some types of NRS design used for evaluating the effects of interventions

13.1.2 Why consider non-randomized studies?

13.1.3 Key issues about the inclusion of non-randomized studies in a Cochrane review

13.1.4 The importance of a protocol for a Cochrane review that includes non-randomized studies

13.1.5 Structure of subsequent sections in the chapter