Table 10.2.a: Publication status of five cohorts of research projects approved by ethics committees or institutional review boards which had been completed and analysed at the time of follow-up. (Adapted from Hopewell et al. (Hopewell 2008).)
|
|
Johns Hopkins University, Baltimore |
National Institutes of Health, U.S.A. |
Royal Prince Alfred Hospital, Sydney |
National Agency for Medicine, Finland |
National Institutes of Health, U.S.A., Multi-centre trials in HIV/AIDS |
|
Reference |
Dickersin 1992 |
Dickersin 1993 |
Stern 1997 |
Bardy 1998 |
Ioannidis 1998 |
|
Period of approval |
1980 |
1979 |
1979-88 |
1987 |
1986-1996 |
|
Year of follow-up |
1988 |
1988 |
1992 |
1995 |
1996 |
|
Number approved |
168 |
198 |
130 |
188 |
66 |
|
Published |
136 (81%) |
184 (93%) |
73 (56%) |
68 (36%) |
36 (54%) |
|
Positive* |
84/96 (87%) |
121/124 (98%) |
55/76 (72%) |
52/111 (47%) |
20/27 (75%) |
|
Negative* |
52/72 (72%) |
63/74 (85%) |
3/15 (20%) |
5/44 (11%) |
16/39 (41%) |
|
Inconclusive/null (if assessed separately) |
Not assessed |
Not assessed |
15/39 (38%) |
11/33 (33%) |
Not assessed |
*Definitions differed by study.